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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T72566 | HIV-1 inhibitor-50 | ||
HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM a... | |||
TP1149 | HIV-1 Rev (34-50) | HIV-1 Rev 34-50,HIV-1 rev Protein (34-50) | HIV Protease |
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-binding domains of Rev in HIV-1. | |||
TN1103 | Diphyllin | ATPase , Proton pump , Influenza Virus , HIV Protease | |
Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. | |||
T76603 | HIV-IN petide | ||
HIV-IN petide is a competitive inhibitor of HIV-1 protease (K i =50 nM) [1] . | |||
T61031 | HIV-1 inhibitor-41 | ||
HIV-1 inhibitor-41 (Compound B23) is an orally active inhibitor of non-nucleoside HIV-1 reverse transcriptase with EC 50 values of 50 nM and 20.8 nM against mutant E138K strain and HIV-1 WT, respectively. HIV-1 inhibitor... | |||
T61311 | HIV-1 inhibitor-30 | ||
HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM.... | |||
T74211 | HIV-1 inhibitor-12 | ||
HIV-1 inhibitor-12 is a potent inhibitor that targets the HIV-1 capsid protein, effectively preventing its polymerization with an inhibition concentration (IC 50) of 9 nM. | |||
T10986 | DDX3-IN-1 | Others | |
DDX3-IN-1 is a DEAD-box polypeptide 3 (DDX3) inhibitor with CC50 of 50 and 36 μM for HIV and HCV, respectively. Antiviral activity. | |||
T60714 | Gp120-IN-2 | ||
gp120-IN-2 (compound 4i) exhibits anti-HIV-1 activity which is a potent inhibitor of HIV-1 gp120 with an IC 50 of 7.5 μM and CC 50 of 112.93 μM. gp120-IN-2 dose-dependently shows cytotoxicity in SUP-T1 cells [1]. | |||
T38727 | Azvudine hydrochloride | RO-0622 hydrochloride,Azvudine hydrochloride,FNChydrochloride | |
Azvudine hydrochloride (RO-0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI) that exhibits strong antiviral effects against HIV, HBV, and HCV. It demonstrates highly potent inhibition of HIV-1 (EC 50 ra... | |||
T60871 | Gp120-IN-1 | ||
gp120-IN-1 (compound 4e) is a potent HIV-1 gp120 inhibitor with an CC 50 of 100.90 μM and IC 50 of 2.2 μM. gp120-IN-1 inhibitis gp120-mediated virus enter into cells. gp120-IN-1 has anti-HIV-1 activity. gp120-IN-1 has do... | |||
T39787 | KRH-3955 hydrochloride | ||
KRH-3955 hydrochloride is a CXCR4 antagonist with oral bioavailability. It effectively inhibits the binding of SDF-1α to CXCR4, exhibiting an IC 50 of 0.61 nM. Additionally, KRH-3955 hydrochloride displays high potency a... | |||
T78925 | HIV-1 inhibitor-58 | ||
HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138... | |||
T72563 | HIV-1 inhibitor-49 | ||
HIV-1 Inhibitor-49, a HEPT analog, is an orally active non-nucleoside reverse transcriptase inhibitor with potent activity against HIV-1, demonstrating an IC 50 of 30 nM. It features an excellent pharmacokinetic profile ... | |||
T78749 | HIV-1 inhibitor-57 | ||
HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficac... | |||
TMA1012 | Ganoderiol F | Androgen Receptor , HIV Protease , Autophagy | |
Ganoderiol F has anti-inflammatory, cytotoxic and anti-HIV activity, it inhibits activity of topoisomerases in vitro, and it inhibits human immunodeficiency virus-1 protease with IC(50) values of 20-40 microM. It induced... | |||
T35762 | MC1742 | ||
MC1742 is an inhibitor of class I histone deacetylases (HDACs; IC50s = 0.1, 0.11, 0.02, and 0.61 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 7 and 40 nM for HDAC6 and HDAC10, respectively).1 ... | |||
T36574 | GW841819X | GW841819X | |
GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X was a single enantiomer but of undefined chirality at the 4-position of the benzodiazepine ring3. GW841819X and JQ1 were recently d... |